Factory Supply High Purity API Silodosin Powder for Dysuria Patient CAS No. 160970-54-7

• CAS No.: 160970-54-7
• Formula: C25h32f3n3o4
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Technical
• Colour: White
• Model NO.: Silodosin
• Application: Anti-Cancer
• MW: 495.53
• Sheif Life: 2 Years
• Storage: Cold Dry Place
• Deliver Time: 7-10 Days
• Samples: Available
• Purity: >98%
• MOQ: 10g
• Transport Package: Discreet Package
• Specification: 1kg/Alu Bag, 25kg/Drum
• Trademark: Lx
• Origin: China
• HS Code: 3824999999
• Production Capacity: 500kg

Product Description

 

Factory Supply High Purity API Silodosin Powder for Dysuria Patient CAS No. 160970-54-7 
 

 

Silodosin is a kind of α- adrenergic receptor antagonists developed by Japanese Kissei pharmaceutical company. It has a very good therapeutic efficacy on treating the dysuria related to benign prostatic hyperplasia. The selective effect on urethra of Silodosin is 12 times and 7.4 times as high as that of prazosin and tamsulosin, respectively, which can significantly inhibit norepinephrine-induced contraction of the prostate; it has dose-dependent inhibition bladder activity excitation in the benign prostatic hypertrophy models of rats, and can also improve the pressure threshold of bladder contraction. These data have suggested that, in addition to helping improve bladder function, silodosin is also effective in alleviating the related symptoms associated with benign prostatic hypertrophy.
Compared with similar drugs such as prazosin and tamsulosin, silodosin has a high selectivity onn theα1A- receptors located in the prostate and bladder neck, while having a low affinity to theα1B- and α1D-receptor. It can block theα1A- receptors in these sites, and relax the smooth muscle, and thus leading to the improvement of urinary flow rate and the alleviation of BPH symptoms.
The selective binding to the α1A-receptor by silodosin has a higher selectivity compared to the binding to the cardiovascular associated receptors α1B, thus maximizing the activity of the target organ as well as minimizing the potential effect on blood pressure.

FUNCTION

1 Silodosin Got a good solve the curative effect of dysuria, also reduced the incidence of hypotension and other adverse reactions.
2 Silodosin can reduce peripheral vascular resistance in other parts of the body to the body of the systolic blood pressure and diastolic pressure is lower

Items	Specification	Results
Appearance	White to off-white crystalline powder	White crystalline powder
Specific Rotation	-17-12°	-14.36°
Loss on drying	NMT1.0%	0.05%
Residue on Igniton	NMT0.2%	0.07%
Related substances	Individual impurity:NMT0.5%	0.15%
	Total impurity:NMT1.0%	0.30%
Heavy Metals	NMT20ppm	Confroms
Assay	NLT99.0	99.63%

 

 

Our Company

Our Advantages:
1.We are very experienced with this field(more than 10 years);

2.Good after-sales service

3.100% quality guaranteed;

4.We accept sample order for testing;

5.Strong supply ability

6.Made in China gold members with high credit guarantee.

Hebei Luoxing Technology Co., Ltd. is located at Shijiazhuang City. It is a professional manufacturer of injection molds, Manufacturers of injection molding processing, product assembly and packaging, existing CNC machining centers, middle wire, slow wire,the company has a team of high-level technicians with more than 20 years of work experience.

Equipped with UG/CAD and other advanced design, technology, three-dimensional modeling and other software to make the CAD/CAE/CAM information of mold manufacturing .

The technology has been applied for delivery, comprehensively improved the mold design ability and processing quality, shortened the mold manufacturing cycle, At the same time, it is equipped with an injection molding machine to realize one-stop mold, injection, and assembly, and provide customers with high-quality services.



Exhibition

 

Q1: Can i get some samples?
A: Yes 

Q2:Payments Methods?
A: Payment by Bitcoin,Credit card, T/T, Western Union Etc.

Q3: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to
pay the shipping cost or arrange a courier to us and take the samples.

Q4:What's your MOQ?
A:Our MOQ is 1g. 

Q5: How about delivery leadtime?
A:About 3-5 working days after payment confirmed. 

Q6:Is there a discount?
A:Different quantity has different discount.

Q7: How do you treat quality complaint?
A:We will send you free goods for replacement or refund your loss.